Specializing in Lyme disease, autoimmune neurological disorders, and complex chronic conditions. Dr. Elena Frid finds answers where others have failed — for both children and adults.
19+ years specializing in infection-induced autoimmune disorders, Lyme disease, and complex neurological conditions — treating patients others couldn't diagnose.
Dr. Frid combines deep neurological expertise with integrative medicine to uncover root causes — successfully treating patients that conventional medicine has failed. She sees both children and adults, with patients traveling from across the US and internationally.
Comprehensive neurological and laboratory evaluation going far deeper than standard workups — uncovering infectious, immune, and toxic triggers.
Every plan is uniquely tailored to your neurological profile, immune function, and history. No cookie-cutter protocols here.
Access to IVIG, SOT, Rituximab, and advanced modalities not offered in standard neurology practices.
You always see Dr. Frid directly — a solo private practice where every patient receives unhurried, personal attention.
Advanced neurological & integrative medicine for complex chronic conditions — delivered with precision in New York City.
Comprehensive diagnosis and treatment of Lyme disease and co-infections (Babesia, Bartonella, Anaplasma) using current evidence-based integrative protocols.
Learn More →Specialized diagnosis and treatment of pediatric autoimmune neuropsychiatric disorders triggered by infection — sudden-onset OCD, tics, anxiety, and behavioral changes in children.
Learn More →Specialized care for autoimmune encephalitis, PANS/PANDAS, Guillain-Barré, and other infection-triggered neurological conditions in adults and children.
Learn More →Supportive Oligonucleotide Therapy using custom RNA molecules to target persistent infections, restore cellular energy, and support neurological healing.
Learn More →IV immunoglobulin therapy to modulate immune response, reduce neuroinflammation, and support recovery from autoimmune and post-infectious conditions.
Learn More →Evaluation and treatment for mycotoxicosis, heavy metals, CIRS, and chronic inflammatory response syndrome with integrative detox protocols.
Learn More →Dr. Frid sees patients with complex, often misdiagnosed conditions that conventional medicine struggles to address. If you've been told "everything looks normal" — there may still be answers.
A methodical, patient-centered path from first contact to lasting recovery.
An in-depth review of your full history, symptoms, prior testing, and timeline to form a complete clinical picture.
Targeted neurological, immunological, and functional lab testing — specialized Lyme panels, autoimmune markers, toxin screening.
A tailored protocol combining advanced therapies, integrative approaches, and lifestyle interventions unique to your case.
Regular follow-up, lab review, and protocol adjustments to track your progress and optimize long-term recovery.
Real experiences from patients who found clarity and recovery with Dr. Frid.
You deserve answers. You deserve care that goes beyond the surface. Dr. Frid and the Leda Medical team are ready to help you find your path to recovery.
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Everything you need to know before your first visit.
Today, Lyme disease is the most commonly reported tick-borne disease in the United States and Europe. Dr. Elena Frid is one of New York City's most experienced neurologists specializing in the diagnosis and treatment of Lyme disease and its neurological manifestations.
Lyme disease is caused by the Borrelia species of bacteria. In the USA, Borrelia burgdorferi causes the majority of cases, while in Europe and Asia Borrelia afzelii and Borrelia garinii carry the greatest burden of disease. The clinical manifestations have been identified as early localized, early disseminated, and late chronic.
The neurological effects of Lyme disease include both peripheral and central nervous system involvement — focal nerve abnormalities, cranial neuropathies, painful radiculoneuritis, meningitis, and toxic metabolic encephalopathy, known as Lyme encephalopathy.
Important: Many patients with chronic Lyme disease have been told their symptoms are "all in their head" or receive a diagnosis of anxiety or depression. Dr. Frid takes a thorough, investigative approach and believes in the validity of these symptoms — working diligently to find and treat the underlying cause.
There are a wide range of neuroinfectious diseases that can present alongside or be triggered by Lyme infection, including:
Lyme disease occurs in three stages: early localized, early disseminated, and late disseminated. However the stages can overlap and not all patients go through all three. A bull's-eye rash is usually considered one of the first signs of infection, but many people develop a different kind of rash or none at all. In most cases, Lyme symptoms begin with a flu-like illness. If untreated, symptoms can continue to worsen and turn into a long-lived debilitating illness.
Symptoms may begin hours to weeks after a tick bite. Lyme is easiest to cure at this stage.
Occurs weeks to months after the tick bite as bacteria begin spreading throughout the body.
Occurs weeks, months, or years after the tick bite if untreated. Bacteria have spread throughout the body, often causing chronic arthritis and neurological symptoms.
People treated with appropriate antibiotics in the early stages of Lyme disease usually recover rapidly and completely. After treatment, a small number of people still have some symptoms such as muscle aches and fatigue — known as post-Lyme disease syndrome. Some experts believe that certain people who get Lyme disease are predisposed to develop an autoimmune response that contributes to their symptoms.
Antibiotics commonly used for oral treatment include doxycycline, amoxicillin, or cefuroxime axetil. People with certain neurological or cardiac forms of illness may require intravenous treatment. In up to 80% of cases, the antibiotic cures the infection. For early disseminated Lyme disease, oral antibiotics are recommended for symptoms such as facial palsy and abnormal heart rhythm. Intravenous antibiotics are recommended for meningitis or more severe heart problems. In late-stage Lyme, a patient may receive oral or intravenous antibiotics.
Note: Treatments in this area are complex and evolving. Dr. Frid stays current with the latest ILADS guidelines and clinical research to ensure every patient receives the most up-to-date, evidence-informed care.
Ticks often carry multiple pathogens simultaneously. Co‑infections can significantly complicate the clinical picture, cause treatment-resistant symptoms, and are frequently missed by standard testing. Dr. Frid evaluates and treats a comprehensive range of tick-borne co‑infections.
While Lyme is the most prevalent tick-borne disease in the U.S., there are a number of other infections transmitted by ticks, pets, animals, and environmental factors. Dr. Frid evaluates and treats the full spectrum of these co‑infections, which are frequently missed by standard testing and can significantly complicate a patient's clinical picture.
The charts below illustrate the overlapping symptom profiles of common co-infections, helping to identify patterns that guide Dr. Frid's diagnostic approach.
Dr. Frid specializes in autoimmune neurological disorders — conditions where the immune system mistakenly attacks the nervous system, often triggered by infections, environmental exposures, or genetic predispositions. She sees both children and adults with complex presentations.
Autoimmune neurological disorders occur when the immune system produces antibodies or inflammatory cells that target the brain, spinal cord, peripheral nerves, or neuromuscular junction. These conditions can be triggered or exacerbated by infections (such as Lyme disease, streptococcal bacteria, or viruses), toxic exposures, or underlying genetic vulnerabilities.
Symptoms range from subtle cognitive changes and psychiatric symptoms to severe seizures, movement disorders, and loss of consciousness. Because many of these conditions are rare and present atypically, they are frequently misdiagnosed as psychiatric illnesses, multiple sclerosis, or dismissed entirely.
Dr. Frid's expertise: She was among the early physicians in the US to recognize and treat infection-induced autoimmune neurological disorders in both pediatric and adult populations — with a particular focus on cases triggered by Lyme disease and streptococcal infections (PANS/PANDAS).
PANS and PANDAS are conditions where children experience a sudden, dramatic onset of neuropsychiatric symptoms. Dr. Frid has treated hundreds of children with these conditions and takes a comprehensive approach that addresses the infectious trigger, immune dysregulation, and neurological symptoms simultaneously.
PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) is a broad category for a sudden onset of neuropsychiatric symptoms, while PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections) is a specific type of PANS triggered by a strep infection. All PANDAS cases are PANS, but not all PANS cases are PANDAS — PANS can be triggered by a wider variety of infections and other factors, whereas PANDAS is exclusively linked to Streptococcus pyogenes.
PANS/PANDAS Population Analysis — Based on 700 family self-reports
PANS is a rare condition that affects children, causing a sudden and significant onset of neuropsychiatric symptoms. Diagnosis requires all three of the following:
The onset of PANS may start with infectious agents other than strep. It also includes onset from environmental triggers or immune dysfunction.
PANDAS is a condition where a child develops sudden or significant changes in neuropsychiatric symptoms following a streptococcal (strep) infection. Clinical diagnosis of PANDAS includes 5 criteria:
Intravenous Immunoglobulin (IVIG) is one of the most powerful tools available for treating autoimmune neurological conditions. Dr. Frid has extensive experience prescribing and managing IVIG therapy for both adult and pediatric patients with complex immune disorders.
This treatment is administered exclusively in Dr. Frid's office, under her direct supervision. No exceptions — for patient safety and optimal care outcomes.
Intravenous Immunoglobulin (IVIG) is a blood product derived from thousands of healthy donors that contains a broad spectrum of antibodies. When infused intravenously, it modulates the immune system, neutralizes harmful autoantibodies, and provides a temporary "reset" that can dramatically reduce neuroinflammation and autoimmune activity.
IVIG has been used for decades and has an extensive safety record. It is FDA-approved for several autoimmune conditions and is used off-label — with substantial clinical evidence — for many others including PANS/PANDAS, autoimmune encephalitis, and post-infectious neurological disorders.
Why IVIG at Leda Medical? Dr. Frid carefully evaluates each patient to determine the appropriate IVIG dosing, frequency, and product — and she monitors patients closely throughout treatment to optimize outcomes and minimize side effects.
IVIG is administered as an intravenous infusion over several hours. Depending on the condition being treated, infusions may be given monthly or more frequently, particularly during the initial phase of treatment. Dr. Frid coordinates infusion scheduling to make the process as convenient as possible.
A precision-medicine approach using custom-designed small RNA molecules to target and suppress specific pathogens — including Lyme disease, Epstein-Barr virus, Babesia, Bartonella, and more. SOT works 24/7 in the body for months after a single infusion.
SOT (Supportive Oligonucleotide Therapy) is an innovative, precision-medicine approach that uses custom-designed small RNA molecules to interfere with the replication of specific pathogens — including Borrelia burgdorferi (Lyme), Epstein-Barr virus, Babesia, Bartonella, and others.
Unlike traditional antibiotics, SOT is highly targeted to the specific genetic sequences of the infecting organism and does not harm healthy cells. It works 24/7 in the body for approximately 3–6 months after a single infusion, continuously suppressing the pathogen.
These therapies are particularly beneficial for patients with:
Over 1 billion people worldwide suffer from neurological disorders. Tissue Nano Particle therapy — powered by MSC-derived exosomes — represents one of the most exciting frontiers in regenerative medicine, offering targeted cellular communication, anti-inflammatory action, and the ability to cross the blood-brain barrier.
Exosomes are so-called extracellular vesicles — tiny "bubbles" released from cells, especially stem cells. They act as shuttles for genetic information and proteins between cells, allowing for intricate cell-to-cell communication. They transport molecules that are important regulators of intracellular information between close and distant cells, carrying instructions that tell cells how and when to react.
Emerging evidence has shown that the paracrine effects of mesenchymal stem cells (MSCs) are mediated by the secretion of these extracellular vesicles. Exosomes are approximately 30 to 100 nm in diameter and are present in body fluids such as blood and cerebrospinal fluid. They harbor proteins, lipids, microRNA (miRNA), and RNA, and have been observed facilitating intercellular communication under various physiological and pathological conditions.
MSC exosomes have shown therapeutic potential in various cancers, strokes, diabetes, cardiovascular disease, autoimmune conditions, Parkinson's disease, Alzheimer's disease, multiple sclerosis, and osteoarthritis.
Exosomes are small signaling proteins derived from cells. While they are not stem cells themselves, the exosomes used in regenerative therapies come directly from stem cells — and contain much of the important signaling pathways found in stem cells. When it became clear that injected stem cells themselves did not engraft and grow into new organs, researchers discovered their remarkable benefits came from cell signaling. MSCs were therefore renamed "master signaling cells."
MSCs stimulate the recipient's own cells — including the native stem cells found in every organ and tissue of the adult body — to differentiate and proliferate. The cells that do the healing are already there; they just need the proper signals. And the most effective way for MSCs to deliver those signals is via exosomes.
MSC-derived exosomes play crucial anti-inflammatory and immunosuppressive roles in immune cells. Their unique properties make them highly effective delivery vehicles:
Exosomes travel intact through the bloodstream and easily cross the blood-brain barrier to reach target organs and tissues — a capability most conventional therapies lack.
Can travel via systemic therapy without risk of clumping. Not perceived as foreign — no immune markers on their surface. Cannot transdifferentiate into other cells or malignant cells.
Deliver miRNA and mRNA directly to target cells. Influence target cells through at least four different mechanisms. Messenger RNA assists other cells in proliferation by inserting missing cell information.
Easy to administer with easily controlled dosage. GMP laboratory grade — screened for disease, viruses, and bacteria before use.
Exosomes carry genetic information, proteins, and messenger RNA. Because of their unique shape and content, they are able to tell cells how and when to react. Exosomes from young stem cells rejuvenate older cells — assisting in calming an overactive immune system or modulating it to respond in a more coordinated and effective fashion.
Exosomes secreted by mesenchymal stem cells contain a diverse array of "signaling molecules" which stimulate growth, healing, and tissue and organ regeneration.
The benefits of exosome therapy vary, but most patients report a reduction of the inflammatory symptoms of their chronic disease — indicating the exosomes are assisting in the repair and regulation process. As time goes on, exosomes will also reprogram cell function and aid in repair processes.
Timeline: It may take up to four to six months to see the full benefit, but results should last as long as 12 months. Patients with degenerative diseases — including Lyme disease, chronic inflammation, and autoimmune disease — will benefit the most from exosome therapy.
Stem cell-derived exosomes have demonstrated anti-inflammatory potential — inducing high levels of anti-inflammatory cytokines. The following conditions are primary candidates for this treatment:
Lyme Disease is a very complex disease caused by the Borrelia burgdorferi bacteria, which compromises the immune system. A combination of factors causes the onset of illness as immune system functions become disrupted — leading to diminishing cellular health, immune function, metabolic function, and dramatically increasing inflammation.
Many Lyme patients have dysfunction of the mast cells, increasing their inflammatory response. Inflammation is a central player in most neurodegenerative diseases as well. Incorporating exosomes into a multimodality treatment regimen may help break the inflammatory cycle and provide the body with necessary cellular information to facilitate healing.
One of the key mechanisms controlling the direction of immune responses is the balance between specific immune cells involved in protection vs. autoimmune responses — the Th17/Treg ratio. Exosomes from mesenchymal stem cells have shown the ability to normalize the Th17/Treg ratio and bring a deviant immune response back to normal, making them particularly valuable in autoimmune conditions.
Research has shown that exosomes can penetrate the blood-brain barrier and stimulate neuronal differentiation, neuronal growth, and suppress inflammatory processes within the brain tissue — offering hope for conditions where conventional treatments struggle to reach.
The starting material (mesenchymal stem cells) is GMP laboratory grade, meaning it has been screened for disease, viruses, and bacteria. This rigorous screening process ensures the highest level of safety for each patient.
This is extremely unlikely, as there are no immune markers on the surface of exosomes. They are not cells or tissue. It may be possible to experience a die-off reaction after receiving exosomes, as these activate natural killer cells to become T-Regulator cells. For this reason, Dr. Frid always administers a small test dose before applying a larger dose.
At Leda Medical: Dr. Frid evaluates each patient individually to determine candidacy for TNP/exosome therapy and stays current with the latest research and clinical trials. Please submit an inquiry to discuss whether this may be appropriate for your case.
Dr. Frid and the team at Leda Medical regularly share educational content on exosomes, TNP therapy, and related topics. Watch the videos below to learn more, and explore the research articles for deeper reading.
Due to complications that often arise from in-home infusion and subsequent nursing issues, and to improve patient outcome of signs or symptoms post infusion, Dr. Frid offers Rituximab treatment in her office only, under her direct supervision.
This treatment is administered exclusively in Dr. Frid's office, under her direct supervision. No exceptions — for patient safety and optimal care outcomes.
Rituximab is a type of drug known as a biological therapy that can reduce inflammation and damage to your joints. It's also known by the trade names MabThera, Rixathon, Ruxience, and Truxima.
Normally, the immune system creates inflammation to protect the body from infections. But in some conditions a group of cells in the immune system, called B-cells, cause unnecessary inflammation which damages the body's healthy tissue.
Rituximab works by lowering the number of these B-cells to reduce inflammation, pain, swelling and joint damage. If rituximab works for you, you'll probably start to feel some improvement after around six weeks.
Rituximab can be prescribed for:
Rituximab won't be started if:
Before you're prescribed rituximab, doctors sometimes use a scoring system to assess how many of your joints are painful or swollen and how it makes you feel. This helps them work out how active your condition is. You'll also need blood tests before treatment to see whether the drug is suitable for you.
It's generally recommended that pregnant women in their second or third trimester should avoid taking rituximab until they have had their baby.
Your doctor may decide not to prescribe rituximab if you have severe heart problems or breathing problems.
Before you are given rituximab you'll have blood tests to check your antibody and B-cell levels. If these levels are low you may be given a smaller dose. Your doctor may also check for previous infections of hepatitis or tuberculosis (TB), as rituximab can increase the risk of these infections starting up again.
Important: If you have HIV you won't be able to take rituximab. People in groups at high risk of HIV infection will be given an HIV test before starting treatment. People who have cancer or who are at high risk of cancer might not be able to take rituximab — your doctor will discuss this with you.
Rituximab is given in a private office through a drip into a vein — known as an intravenous infusion. This is done by a doctor or nurse so they can monitor you for any side effects while you're receiving treatment.
The first infusion takes around six hours, but later infusions may be faster. Usually, you'll start treatment with two infusions given two weeks apart. The infusions are then repeated when the improvement is wearing off, or to prevent a flare-up of symptoms — anywhere from six months to a few years later.
On the day of your infusion, you'll typically receive steroids along with paracetamol and an antihistamine. Between infusions, you'll have blood tests and see a specialist doctor or nurse to check how you're getting on.
Rituximab was originally only available as MabThera. More recently, three biosimilar versions — Truxima, Ruxience and Rixathon — have become available. These work in a similar way to the original. New versions of biologic drugs are becoming available all the time, so you may be prescribed rituximab under a different name.
A few people feel unwell or experience a fever, wheeziness, a rash, or a fall in blood pressure during or shortly after the infusion. If you start feeling unwell during your infusion, tell the person giving it to you — they can slow the infusion rate so the drug enters your body more gradually.
Rituximab affects your immune system, which can make you more susceptible to some infections. Tell your doctor or nurse straight away if you develop any new symptoms such as a sore throat, fever, or other signs of infection. You should also see your doctor if you develop chickenpox or shingles, or come into contact with someone who has them.
After three or four courses of rituximab, the levels of protective antibodies in your blood may go down, which might increase your risk of infection. Your doctor will discuss this with you before deciding on further treatment.
Rare but serious: Very rarely, patients treated with rituximab can develop progressive multifocal leukoencephalopathy (PML), which can damage the brain and spinal cord. See your doctor straight away if you notice pins and needles, weakness, shaky movements, sight loss, speech problems, changes in behaviour or mood, or difficulty moving your face, arms or legs.
Rituximab is often given alongside other drugs, including methotrexate and steroids. Discuss any new medications with your doctor before starting them, and tell anyone treating you that you've had rituximab. It's recommended that you carry a biological therapy alert card so that anyone treating you will know your antibody levels may be low.
People on rituximab should avoid live vaccines. You should speak to your doctor before starting treatment if you think you might need a live vaccine against illnesses such as BCG, yellow fever, or MMR. Most live vaccines should be given at least a month before you start rituximab. Vaccines for flu and pneumonia, which are not live vaccines, can be given at least one month before your next course.
If you need an operation, it will usually be scheduled at least three months after your last infusion. Make sure your surgeon knows you're on rituximab.
You can drink alcohol while on rituximab, but keep within the recommended limits of no more than 14 units per week. Try to have alcohol-free days and don't save up units to drink in one go.
It's generally recommended that rituximab be stopped six months before pregnancy. However, if you have recently had rituximab and find yourself pregnant, it is not thought to be harmful to your baby. It is considered safe to take rituximab while breastfeeding, and for men to continue taking rituximab while trying to father a child. Speak to your doctor about any concerns.
Mold exposure and environmental toxins can cause profound neurological, immune, and systemic illness — yet these diagnoses are frequently overlooked. Dr. Frid is experienced in diagnosing and treating mold toxicity, Chronic Inflammatory Response Syndrome (CIRS), and heavy metal toxicity with a comprehensive integrative approach.
Mold toxicity — also known as mycotoxicosis — occurs when the body accumulates mycotoxins from mold-contaminated environments (typically water-damaged buildings). Unlike a simple mold allergy, mycotoxin illness represents a true toxic exposure that can trigger a systemic inflammatory response affecting the brain, immune system, hormones, and virtually every organ system.
Chronic Inflammatory Response Syndrome (CIRS) is a multi-system, multi-symptom illness caused by ongoing exposure to biotoxins — most commonly from water-damaged buildings (mold), but also from Lyme disease, certain algae toxins, or other biological sources. It is driven by HLA-DR genetic susceptibility and results in a dysregulated immune response that fails to clear the toxins naturally.
Key insight: 25% of the population carries an HLA-DR gene variant that prevents the body from effectively clearing biotoxins. These individuals are at significantly higher risk of developing CIRS and often remain sick for years without proper diagnosis.
Chronic exposure to heavy metals (mercury, lead, arsenic, cadmium) — through dental amalgams, contaminated water, diet, or occupational exposure — can cause neurological damage, immune dysfunction, and chronic illness that mimics many other conditions. Dr. Frid evaluates for heavy metal burden and develops targeted chelation and detoxification protocols.
Functional medicine asks why — not just what. Dr. Frid uses an evidence-based integrative approach that combines the best of conventional neurology with advanced functional medicine testing and therapies to treat the root causes of complex chronic illness.
Conventional medicine excels at treating acute illness and managing symptoms with medications. Functional medicine goes deeper — seeking to understand the root causes of chronic disease by examining genetics, infections, inflammation, nutrition, hormone balance, gut health, environmental exposures, and mitochondrial function as interconnected systems.
Dr. Frid trained as a board-certified neurologist and has integrated decades of functional medicine principles into her practice. She uses this lens to understand why patients are sick — and to design treatment strategies that address those root causes rather than simply suppressing symptoms.
A different kind of doctor: Most patients who come to Dr. Frid have already seen multiple specialists. She excels at synthesizing complex medical histories, identifying missed diagnoses, and creating cohesive treatment plans that address the full picture of a patient's health.
A complete reference guide to the conditions treated at Leda Medical. Each entry includes a brief plain-English summary to help you understand what each condition involves.
Board-Certified Neurologist · Clinical Neurophysiologist · Pioneer in Infection-Induced Autoimmune Neurology. Over 19 years of solo private practice in New York City — dedicated to finding answers for patients others have failed.
Dr. Elena Frid is a Board-Certified Neurologist and Clinical Neurophysiologist based in New York City, widely regarded as one of the nation's leading experts in infection-induced autoimmune neurological disorders. She sees both children and adults with complex cases of Lyme disease, tick-borne co-infections, autoimmune encephalitis, PANS/PANDAS, and other conditions that conventional medicine frequently misses or misdiagnoses.
After finishing her training, Dr. Frid opened her private neurology practice in New York City in 2011. Early on she noticed a pattern: a growing number of patients with peculiar neurological presentations — intractable headaches, visual disturbances, cognitive decline, balance disorders, and complex psychiatric symptoms — who had been evaluated by multiple specialists and remained without a clear diagnosis. When her patients began mentioning Lyme disease, Dr. Frid listened. She attended ILADS conferences, immersed herself in the emerging science of infection-induced autoimmune disorders, and dedicated her practice to this underserved population. She has never looked back.
Most of the important things in the world have been accomplished by people who have kept on trying when there seemed to be no hope at all.
Dr. Frid approaches every patient as a unique clinical puzzle. She brings the methodical rigor of a neurologist — EMG, EEG, lumbar puncture, advanced neuroimaging — together with the broad lens of functional and integrative medicine. Her diagnostic process is exhaustive, her treatment plans are individualized, and her follow-through is relentless.
She is widely recognized for her willingness to take on the most complex, previously undiagnosed cases — and for validating the experiences of patients who have been dismissed by the medical system. Many of her patients describe their first appointment with Dr. Frid as the first time a physician truly listened to them.
Watch Dr. Frid discuss Lyme disease, autoimmune encephalitis, and complex neurological illness across interviews, podcasts, and her own YouTube channel — "Lyme Talk with Dr. Frid."
Having worked with Dr. Frid, I have great respect for her knowledge and ability to handle complicated illness. Whenever I feel I need assistance managing my patients, I refer them to her for further care. She is truly one of the best in the field.
Real stories from patients whose lives were changed.
Trusted by Dr. Frid's patients · Supporting neurological & immune health
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Dr. Frid has been wonderful with our PANDAS-inflicted son. It took several years, but she stuck with us and, ultimately, found a way to practically cure him! Highly recommend. She is expensive, but worth it; the office staff willingly works with you to find ways to make the magic happen.
Dr. Frid is an excellent, patient-focused doctor. She helped to diagnose and treat a condition that other doctors couldn't, and we went to more than a few. She is a wonderful listener, and we can't recommend her highly enough.
Dr. Frid was amazing helping me identify challenges that every other doctor thought were just in my head. She always spent a lot of time with me, was very responsive and generally a pleasure to see. I would recommend her to anyone concerned with exposure to tick borne illnesses.
Dr. Frid made me better when all the other doctors I saw couldn't figure out what was going on. She is a genius who has improved the quality of my life so much and I'm forever grateful to her and excited to continue my healing journey under her care. Shout outs also to Christine, Ashley, Claire and Alex in her office for being so kind, thoughtful and caring.
Dealing with active infections for over 11 years, Dr. Frid is the first practitioner to actually look me in my eyes as we discuss symptoms and plans for action. Her knowledge of not only my diseases/conditions but other conditions that closely interact with them are incredible and priceless. Dr. Frid listens to the nuances of your specific problems and creates plans based on your individualities. If you are looking to be heard and to get off the killer antibiotic train — see Dr. Frid!
Dr. Frid has been life changing. She listens intently to her patients with care and tailors the treatment. She has truly changed the quality of my life. I am forever grateful to have a doctor that I trust so much!
My daughter has been a patient of Dr. Frid for the past four years. Dr. Frid and her team are a safe haven for patients with PANS, PANDAS, Lyme and other diseases that the vast majority of specialists are not interested in or not prepared to treat. We are fortunate to have Dr. Frid leading my daughter's treatment, and as a family, we are thankful for her dedication and expertise in treating complex illnesses.
There is no doubt that Dr. Frid saved my life. I had been sick for almost two years before I met her — brain fog, joint pain, blood pressure totally out of control. I had seen my primary doctor and several specialists; they all said they didn't know what was wrong. Dr. Frid diagnosed Bartonella on the first appointment and Lyme when the specialized test came back. She treated me for both. I am well today thanks to Dr. Frid.
Dr. Frid has been treating my daughters in an amazing way — not only as a doctor, but as a fantastic and incredible human being. We feel blessed to have chosen her as our doctor because of her expertise and incredible ability to make you feel comfortable with treatments and challenges.
"Thank you so much for everything. My last appointment with you relieved our fears in a big way and like always, I cherish the amazing doctor that you are. Mark and I say every single day how in awe we are. He has come so far that it's just amazing. We owe so much to you that I don't even have the words to properly thank you. You helped our son get his life back and for that I'm eternally grateful."
Dr. Frid SAVED MY LIFE! After too many doctors to list misdiagnosed me, Dr. Frid diagnosed me with Bartonella, Babesia & Lyme. Almost 2 years of treatment and I feel better than I have in 20 years. She is the ONLY doctor you should see if you have Lyme and/or co-infections. It's the best decision I ever made.
My personal experience navigating chronic conditions along with dozens of unexplained symptoms has been the biggest struggle I've faced. After countless visits to specialists who treated each symptom in isolation, since meeting with Dr. Frid my status has improved drastically. I no longer seek out other specialists since many of the ailments have been resolved. I was very fortunate to find a doctor with great knowledge and just as importantly, the capacity to listen and understand the significance of details others may dismiss.
Dr. Frid is the best!!! My daughter has recovered 100% because of Dr. Frid. She never looked at us with sad eyes seeing only the brokenness — it was clear we were all working towards the same goal of complete healing. She has a very clear plan for treatment tailored to each specific patient. We never felt alone in this recovery. After missing 2.5 years of school, my daughter is now back better than ever enjoying life as she did before this illness.
Dr. Frid is an awesome doctor who is extremely compassionate. She takes the time to listen to all my concerns. Due to Dr. Frid's comprehensive, thorough care, I am able to maintain my independence and work at a job I love despite having health challenges. Everyone on "Team Dr. Frid" is very kind and supportive — especially on IVIG days.
I came to Dr. Frid because my daughter had been misdiagnosed for over a year — she was probably our last hope. My 12-year-old had been through hell and the doctors in Florida were not competent enough to help. We were at several top children's hospitals. Dr. Frid was the only doctor to listen and do a thorough exam. She noticed what was wrong during the initial exam and then ordered further testing. She is an amazing doctor and I would highly recommend her if you're at your wits' end with no answers.
Ready to start your healing journey with Dr. Frid?
Dr. Frid's published research, conference presentations, and clinical insights — contributing to the advancement of neuroimmunology and integrative medicine.
Original research and clinical reports authored by Dr. Frid.
This presentation explores the clinical overlap between persistent Lyme disease and autoimmune encephalitis — a condition where the immune system attacks the brain in response to infection. Dr. Frid outlines diagnostic criteria, including antibody panels and neuroimaging, and presents treatment protocols combining antimicrobial therapy with immunomodulation (IVIG, steroids) to address both the infection and autoimmune response simultaneously. The work highlights how many patients diagnosed with "post-treatment Lyme disease syndrome" may actually have a treatable autoimmune component that, when identified, dramatically improves outcomes.
This peer-reviewed study examines the relationship between peripheral vascular disease and nerve damage, using serial EMG and nerve conduction studies to track neuropathy progression over time. The research demonstrates how vascular insufficiency directly impacts nerve function and highlights the importance of early electrophysiological monitoring for at-risk patients. The findings have clinical implications for the management of diabetic and atherosclerotic patients with unexplained neuropathic symptoms.
This publication reviews the spectrum of neurological complications arising from hematologic malignancies, including central and peripheral nervous system involvement. It covers cranial neuropathies, leptomeningeal disease, and paraneoplastic syndromes — providing a clinical framework for early neurological assessment in oncology patients. The paper emphasizes the need for neurologists to maintain a high index of suspicion when evaluating patients with known or suspected blood cancers presenting with neurological symptoms.
This case report documents a rare clinical presentation where acute inflammatory demyelinating polyneuropathy (AIDP, a form of Guillain-Barré syndrome) was followed by bilateral brachial neuritis in the same patient. The report discusses the possible shared autoimmune mechanisms, the role of molecular mimicry, and the implications for treatment sequencing in complex neuroimmunological cases. This case adds to the growing body of evidence that autoimmune neurological conditions can occur in overlapping, sequential patterns.
Invited talks and presentations at national medical conferences.
Dr. Frid presented her clinical findings on infection-induced autoimmune encephalitis to an international audience of Lyme-literate physicians. Her talk covered diagnostic challenges, the role of anti-neuronal antibodies, and real-world treatment outcomes using combined antimicrobial and immunomodulatory approaches. The presentation was well-received and contributed to a growing recognition of autoimmune encephalitis as a common complication of persistent Lyme disease.
Dr. Frid was invited to speak at Mt. Sinai Hospital's psychotherapy faculty conference on the neurological underpinnings of psychiatric symptoms — specifically how infections like Lyme disease and Bartonella can mimic or trigger anxiety, OCD, depression, and psychosis. The presentation emphasized the importance of cross-disciplinary collaboration between neurologists and psychiatrists, and the need to rule out infectious and autoimmune causes before attributing symptoms to purely psychiatric diagnoses.
Clinical insights and educational content from Dr. Frid — coming soon.
New articles and blog posts are on the way.
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We believe every patient deserves clarity about the financial side of their care. Below you'll find everything you need to know about the types of insurance we work with, how certain treatments are billed, and what to expect.
At Leda Medical, we work to maximize your insurance benefits wherever possible. The majority of clinical work, treatments, and procedures can be submitted to your insurance for potential coverage — based on your plan's determination and approval. Below is a clear breakdown of what typically falls under each category.
Subject to patients individual insurance benefits and approval, here are some common procedures and treatments that may be covered by your insurance:
Medical Authorization Required: IVIG and Plasmapheresis require prior medical authorization from your insurance company before treatment is given. Our office team will assist you in understanding the authorization process and what documentation is needed.
Billed directly by the patient to their insurance as claims:
Claim reimbursement is subject to patients individual insurance benefits and approval.
The following are not covered by insurance and are the patient's out-of-pocket responsibility:
If insurance does not cover a prescribed medication or procedure, the patient will be informed in advance and the cost will be discussed before proceeding.
Leda Medical is an out-of-network practice. We work with a wide range of insurance plans and provide the documentation you need to seek reimbursement from your insurer.
Wondering what's covered? Reach out to our patient coordinator — we'll help you understand your coverage before your visit.
Patients with PPO plans typically have out-of-network benefits that can be applied toward consultations and services at Leda Medical. We recommend verifying your out-of-network deductible and reimbursement rate before your visit.
*Please check with our office prior to booking an appointment to determine what coverage and benefits you have. This will help you understand the potential treatment cost.
As an out-of-network provider, we accept most major insurance carriers that offer out-of-network benefits. We provide a detailed superbill after each visit that you can submit directly to your insurance company for reimbursement.
*Please check with our office prior to booking an appointment to determine what coverage and benefits you have. This will help you understand the potential treatment cost.
Leda Medical does not accept or work with Medicare or Medicaid plans. Any patient who is a Medicare or Medicaid beneficiary and chooses to be seen by Dr. Frid is required to sign a Medicare Opt-Out Contract prior to their appointment. This contract acknowledges that the patient is knowingly choosing to seek care from an outside coverage physician and that neither Dr. Frid nor Leda Medical will bill Medicare or Medicaid for any services rendered.
Patients who prefer not to use insurance may pay privately. We offer transparent pricing and are happy to discuss payment arrangements to ensure care remains accessible to those who need it.
Health Savings Accounts (HSA) and Flexible Spending Accounts (FSA) are accepted for eligible medical expenses. Our services generally qualify — we recommend checking with your plan administrator to confirm eligibility.
For all visits, Leda Medical provides a comprehensive superbill with all required diagnostic and procedure codes, designed to streamline your out-of-network reimbursement claim submission.
Some advanced therapies offered at Leda Medical have unique billing structures. Please review carefully before beginning a treatment plan.
IVIG therapy at Leda Medical is billed based on your out-of-network insurance benefits. Coverage and reimbursement rates vary depending on your individual plan.
SOT therapy is considered an experimental treatment by most insurance carriers and is therefore not covered by insurance at this time.
Rituximab is a powerful biologic medication used for severe or refractory autoimmune neurological conditions. It is administered exclusively in-house under Dr. Frid's direct supervision — no exceptions.
Follow these steps to make the most of your out-of-network benefits.
Call the member services number on the back of your insurance card and ask about your out-of-network deductible, co-insurance percentage, and reimbursement process for specialist visits.
Contact our office to schedule a consultation with Dr. Frid. Let us know your insurance information upfront so we can assist with any prior authorization or documentation needs.
After each appointment, we provide a detailed superbill with all required diagnosis and procedure codes to file your out-of-network claim.
Submit your superbill to your insurance company using their standard out-of-network claims process. Our team is available to answer any questions that arise.
Our team is here to help you navigate the insurance process. Reach out before your appointment and we'll clarify your benefits and what to expect.
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Last updated: April 26, 2026
Leda Medical, PLLC ("we," "our," or "us") is committed to protecting your privacy. This Privacy Policy explains how we collect, use, disclose, and safeguard your information when you visit our website ledamedical.com, including any other media form, media channel, mobile website, or mobile application related or connected thereto.
We may collect information about you in a variety of ways including:
Personal Data: Name, email address, telephone number, mailing address, and any other information you voluntarily submit through our contact or inquiry forms.
Payment Data: When you make a purchase through our online store, payment information is processed securely through Square. We do not store credit card numbers or payment credentials on our servers.
Health Information: Any health-related information you voluntarily provide when submitting an inquiry or contacting our office. This information is treated with the highest level of confidentiality.
Usage Data: Information your browser sends whenever you visit our website, such as your IP address, browser type, pages visited, and time spent on pages.
We use the information we collect to: respond to your inquiries and schedule appointments; process and fulfill orders placed through our online store; send administrative information such as appointment confirmations; improve our website and services; comply with legal obligations; and protect against fraudulent or illegal activity.
Leda Medical, PLLC is committed to protecting the privacy of your health information in accordance with the Health Insurance Portability and Accountability Act (HIPAA). Any protected health information (PHI) shared with our practice is handled in strict accordance with HIPAA regulations. Our website contact forms are not intended to transmit PHI — please contact our office directly for all health-related communications.
We do not sell, trade, or rent your personal information to third parties. We may share your information with trusted third-party service providers who assist us in operating our website and conducting our business (such as payment processors and email services), provided those parties agree to keep this information confidential.
Our website may use cookies to enhance your experience. You can choose to disable cookies through your browser settings, though this may affect certain functionality of the website.
We implement appropriate technical and organizational security measures to protect your personal information. However, no method of transmission over the Internet or method of electronic storage is 100% secure.
Our website may contain links to third-party websites. We have no control over the content, privacy policies, or practices of any third-party sites and encourage you to review their privacy policies.
Our website is not directed to children under the age of 13. We do not knowingly collect personal information from children under 13. If you believe we have inadvertently collected such information, please contact us immediately.
You have the right to access, correct, or delete your personal information we hold. To exercise these rights, please contact us at the information provided below.
We reserve the right to update this Privacy Policy at any time. Changes will be posted on this page with an updated revision date.
If you have questions about this Privacy Policy, please contact us at:
Leda Medical, PLLC
12 E 44th St. 4th FL, New York, NY 10017
Phone: (212) 288-8832
Last updated: April 26, 2026
By accessing and using this website, you accept and agree to be bound by these Terms of Service. If you do not agree to these terms, please do not use this website.
The content on this website is provided for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay seeking it because of something you have read on this website.
Use of this website or submission of an inquiry form does not create a doctor-patient relationship between you and Dr. Elena Frid or Leda Medical, PLLC. A doctor-patient relationship is only established upon an in-person or telehealth consultation and mutual agreement to proceed with care.
All purchases made through our online store are subject to the following conditions: All sales are final unless the product is damaged or defective upon arrival. Products are medical-grade supplements intended for adults. Consult your physician before using any supplement, especially if you are pregnant, nursing, or taking medications. We reserve the right to refuse or cancel any order at our discretion.
Orders are processed within 2-3 business days. Free shipping is available on orders over $200 within the United States. Delivery times vary by location. We are not responsible for delays caused by shipping carriers.
All content on this website including text, graphics, logos, images, and software is the property of Leda Medical, PLLC and is protected by applicable copyright and intellectual property laws. You may not reproduce, distribute, or create derivative works without express written permission.
Leda Medical, PLLC shall not be liable for any indirect, incidental, special, consequential, or punitive damages resulting from your use of or inability to use this website or its content. Our total liability shall not exceed the amount paid by you for any products or services obtained through the website.
You agree to indemnify and hold harmless Leda Medical, PLLC, its officers, directors, employees, and agents from any claims, damages, or expenses arising out of your use of the website or violation of these Terms.
These Terms of Service shall be governed by and construed in accordance with the laws of the State of New York, without regard to its conflict of law provisions. Any disputes shall be resolved in the courts of New York County, New York.
We reserve the right to modify these Terms of Service at any time. Continued use of the website after changes constitutes acceptance of the new terms.
If you have questions about these Terms of Service, please contact us at:
Leda Medical, PLLC
12 E 44th St. 4th FL, New York, NY 10017
Phone: (212) 288-8832